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About Mesotheliomai Center

About Mesotheliomai Center

Mesothelioma-center.blogspot.com  is web for  information resource for individuals who have been diagnosed with mesothelioma and their families. Our mission, as a leading authority on this topic, is to continually provide relevant, timely, and factual information about asbestos exposure and its causal links to mesothelioma cancer.

Our editorial team is comprised of a group of dedicated professionals committed to making Mesothelioma.com a comprehensive source of support, educational information and inspiration for those suffering from asbestos-related illness. We are grateful for being able to serve in this way and will continue to honor our commitment to being the web's most trusted asbestos and mesothelioma information resource.

Peritoneal Mesothelioma

Peritoneal Mesothelioma - Malignant peritoneal mesothelioma is a rare type of cancer that occurs in the thin cell walls which surround the abdominal cavity, known as the peritoneum. This thin membrane acts a lubricant within the abdominal cavity so that surrounding organs and internal body structures may contract and expand within their normal body function. Incidence of peritoneal mesothelioma is quite rare, and typically presents in less than 500 individuals in the United States each year.

Peritoneal Mesothelioma
Malignant peritoneal mesothelioma is a rare type of cancer that occurs in the thin cell walls which surround the abdominal cavity, known as the peritoneum. This thin membrane acts a lubricant within the abdominal cavity so that surrounding organs and internal body structures may contract and expand within their normal body function. Incidence of peritoneal mesothelioma is quite rare, and typically presents in less than 500 individuals in the United States each year.

 Peritoneal Mesothelioma
Peritoneal MesotheliomaGet This Image For Your Site
Other types of mesothelioma include the more common malignant pleural mesothelioma, occurring in the chest wall membrane surrounding the lungs, and malignant pericardial mesothelioma, which occurs in the pericardial lining of the heart. Peritoneal mesothelioma is the second rarest form of the disease and accounts for approximately 20% of all mesothelioma cases each year.

What Causes Peritoneal Mesothelioma?
Peritoneal mesothelioma is known only to be caused by exposure to asbestos, a microscopic natural fiber that was used heavily in industry. Asbestos is said to reach the abdominal wall by one of two methods. The first is through ingested asbestos fibers which are processed through digestion and become lodged in the peritoneum. The other method is through the lungs and lymph nodes, by inhaled asbestos fibers. Malignant mesothelioma of the pleura is also known to metastasize directly into the abdominal cavity if its spread is not slowed.

Many of those who have worked with asbestos materials have developed peritoneal mesothelioma as a result of exposure to friable asbestos fibers. Asbestos was used in myriad industrial materials and construction products. Exposure to asbestos was common in aluminum plants, steel mills, power plants, and naval shipyards.

Peritoneal mesothelioma is a relatively rare disease, with only 200-500 diagnoses each year in the United States being documented. Risk however, is sustained in those who have been exposed to asbestos. Even those exposed many years ago are potentially at risk for the development of malignant peritoneal mesothelioma. Latency between exposure to asbestos and the development of peritoneal mesothelioma symptoms can be anywhere from 20-50 years. Misdiagnosis is also common because peritoneal mesothelioma symptoms closely mimic minor stomach/abdominal discomfort and hernia. Nevertheless, those with clear asbestos exposure history should be aware of the disease and speak with their doctor or cancer specialist if they believe they may be experiencing symptoms related to mesothelioma.
How is Peritoneal Mesothelioma Treated?

Prognosis of mesothelioma patients is poor, and peritoneal mesothelioma patients are no exception. Most peritoneal treatment regimens for patients include palliative methods such as mesothelioma chemotherapy and radiation therapy. However, if the disease is diagnosed in its earlier stages, patients such as those diagnosed with stage 1 mesothelioma, may be eligible for surgical resection of the disease, which could potentially add years to the initial prognosis.

Surgery is possible for patients diagnosed with earlier-stage disease. Some surgical options include peritonectomy and palliative procedures. Certain physicians, including Dr. David Sugarbaker of the International Mesothelioma Program at Brigham and Women’s Hospital in Boston, MA, have become extremely well versed and experienced in the surgical treatment of malignant mesothelioma. In many cases, surgical treatment for mesothelioma will be coupled with chemotherapy or radiation therapy regimens.

Chemotherapy is the most common treatment for mesothelioma disease. Currently, there is only a single chemotherapy regimen (Alimta® (pemetrexed) in conjunction with Cisplatin) approved by the Food and Drug Administration as a prescribed therapy for the treatment of malignant pleural mesothelioma. There are however, dozens of clinical trials being conducted for mesothelioma patients experimenting with new drugs, including Gemcitabine, Navelbine, Onconase, and others for the treatment of malignant peritoneal mesothelioma.

How is Peritoneal Mesothelioma Diagnosed?
Doctors may suspect peritoneal mesothelioma if the patient complains of stomach, chest, or abdominal pain. Suspicious hernias may actually be a peritoneal effusion caused by peritoneal tumor growth. Misdiagnosis is common and patients will likely undergo multiple imaging scans and a diagnostic biopsy before an official diagnosis is made.

Diagnostic procedures in which fluid is extracted from the peritoneum for lab testing are the only way to conclusively diagnose peritoneal mesothelioma. Samples will be examined for the presence of malignant cells. Once malignant cells are detected, further testing will be needed to classify these cells as malignant mesothelioma.
What are a patient's options?
Patients of peritoneal mesothelioma may be eligible for financial compensation if they were harmfully exposed to asbestos. For additional information on your legal rights regarding mesothelioma please fill out the brief form on this page.

Pericardial Mesothelioma

Pericardial Mesothelioma - Malignant mesothelioma is a type of cancer that originates in the mesothelium, a thin wall of cells that surround the body's organs and internal structures. Pericardial mesothelioma originates in the lining of the heart. Other locales of the disease are malignant pleural mesothelioma, which occurs in the lining of the lungs and malignant peritoneal mesothelioma, which occurs in the abdomen wall. Pericardial mesothelioma is the rarest of these malignancies and accounts for only an estimated 10 percent of all mesothelioma incidences annually.

Pericardial mesothelioma is an asbestos cancer, meaning it's only known cause is asbestos exposure. Asbestos is a naturally occurring, but toxic, mineral that was used in industrial capacities. While the precise route by which microscopic asbestos fibers reaches the pericardial lining is not known, mesothelioma doctors surmise that inhaled asbestos fibers are absorbed into the bloodstream and become entangled in the heart's lining as the blood processes through the heart. Malignant mesothelioma occurring in other parts of the body, such as in the pleura or peritoneum, can also metastasize to the pericardial lining.

How is Pericardial Mesothelioma Treated?
Prognoses are poor in cases of pericardial mesothelioma, just as nearly every mesothelioma prognosis is. However, several treatment options exist to help patients manage the disease and maintain comfort. Chemotherapy and radiation therapy are the most likely mesothelioma treatment options for patients of this disease. Mesothelioma surgery is typically not an option because of the location of the disease and the risk of grave damage to the tumor area.

How is Pericardial Mesothelioma Diagnosed?
Physicians will often suspect pericardial mesothelioma diagnosis if the patient has trouble breathing, shortness of breath, or chest pain. A comprehensive diagnostic and biopsy process will be undergone through use of multiple body imaging scans.
What are a Patient's Options?
Patients of pericardial mesothelioma may be eligible for financial compensation if they were wrongly exposed to asbestos. Anyone who worked with asbestos products is potentially at-risk and should fill out the brief form on this page to receive additional treatment and legal information.

Pleural mesothelioma

Pleural mesothelioma is a rare cancer often diagnosed in people who have been exposed to high levels of asbestos. The malignancy affects the pleura, a thin membrane of lubricating cells that lines the lungs and chest wall. It sometimes takes 10 years or more for changes to appear that are indicative of pleural disease, and even long for symptoms to manifest. These differences can include a thickening or calcification of the pleural lining, a condition commonly diagnosed as pleural plaques. Conditions like pleural calcification or the development of pleural plaques often serve as pre-cursor to mesothelioma.

In most instances, pleural disease is not considered fatal but it can cause diminished lung function and may confirm that a person has sustained significant asbestos exposure. Those diagnosed with pleural conditions are generally considered to be at a higher risk for developing the more severe pleural mesothelioma.


Pleural mesothelioma originates in the pleura but can quickly spread to the outer chest wall, abdomen, and heart. Pleural mesothelioma is typically fatal within 1 year of diagnosis. However, understanding and recognizing key risk factors, like asbestos exposure, will typically lead to early detection of the cancer. Those who are fortunate to receive an early diagnosis are likely to be more eligible for life-sustaining treatments such as surgical resection of the cancer. This type of treatment can extend a patient’s life years beyond that of a typical mesothelioma patient.

Pleural mesothelioma
Pleural mesothelioma
While there is no cure for pleural mesothelioma, treatment options do exist for the cancer. There are ways for patients to manage the disease through tumor management including traditional radiation and chemotherapy methods, which can ease symptoms of the disease and make a patient more comfortable. In patients where a diagnosis is made of early stage disease, mesothelioma surgery can extend the survival rate far beyond previous levels in untreated disease.
Treatment and Tumor Management

Nearly all patients diagnosed with pleural mesothelioma are able to receive some form of treatment for their illness. While there is currently no cure for mesothelioma, patients have been able to extend initial prognosis through advanced mesothelioma treatment regimens currently being developed at clinics and cancer centers across the United States.
Surgery

Surgical resection is difficult in pleural mesothelioma patients when the disease is diagnosed in later stages because at that time the tumor has typically metastasized to other areas of the body like the abdominal cavity and lymph nodes. However, in early stage diagnoses, surgery can absolutely be utilized to slow the advance of mesothelioma disease.

Common surgical procedures utilized in the management of malignant mesothelioma are pneumonectomy and extrapleural pneumonectomy. Pneumonectomy is a general procedure utilized not only in patients of malignant mesothelioma, but also for those battling lung cancers or related lung conditions. Pleurectomy involves the removal of a either a portion of or the entire affected lung in patients. Extrapleural pneumonectomy is a more comprehensive procedure that is more tailored to mesothelioma patients and involves the removal of the entire affected lung, the pleura, the diaphragm, and the pericardium, which is the mesothelial lining that surrounds the heart cavity.
Chemotherapy

Chemotherapy is likely the most prevalent treatment utilized by patients of malignant pleural mesothelioma. While several different chemotherapy drugs have been utilized to varying degrees of effectiveness for the management of malignant pleural mesothelioma, only one has been approved by the Food and Drug Administration as a prescribed therapy for the treatment of malignant pleural mesothelioma. A combination of Alimta(Pemetrexed) and Cisplatin is currently the only drug combination in approved status. However, several other clinical trials are currently active attempting to determine the effectiveness of other drugs including Gemcitabine, Navelbine, and Onconase.
Radiation Therapy

Radiation therapy has been utilized in the treatment of many types of cancer and pleural mesothelioma is no different. Often, radiation is not able to manage cancer by itself so it is combined with either surgery, chemotherapy, or both to augment the treatment plan as a whole. Radiation therapy for pleural mesothelioma utilizes external beam radiation to mutate tumor cells within the body and slow their growth and spread.
Alternative and Complementary Therapies

A growing school in cancer care involves integrative approaches to the treatment of cancer. Integrative oncology utilizes not only the conventional therapies discussed above, but also untraditional therapies such as acupuncture, massage, and reflexology to assist the patient in managing pain, anxiety, and restlessness. Patients battling pleural mesothelioma have effectively utilized alternative therapies like these to increase the effectiveness of their treatment program overall. Generally, patients who are able to withstand the difficult side-effects of more potent chemotherapy and radiation treatments will be best able to extend their prognosis. Patients of pleural mesothelioma who have utilized alternative therapies have been able to do just that. However, most of these therapies are preferential and will depend on the health of the patient as to whether or not they will be able to engage in them. As with any treatment, patients should seek the consultation of their oncologist or cancer specialist before engaging in any alternative therapy.
What Causes Pleural Mesothelioma?

Pleural mesothelioma is known only be caused by exposure to asbestos. Asbestos is a naturally occurring and microscopic mineral that was used for hundreds of years in a number of different industrial compounds. Asbestos fibers are extremely durable, but also extremely difficult to expel from the body once introduced to the internal tissue.

Upon inhalation, asbestos fibers will lodge on the outer layers of the lung tissue and within the pleura, a thin membrane of mesothelial cells which lines the chest cavity. This lining allows for the free movement of the body’s internal body structures because it provides a special lubrication to the surface of these structures. The pleura, like other mesothelial membranes, is a delicate structure and microscopic asbestos fibers can cause pleural plaques to form on its surface. Pleural plaques may eventually develop into pleural mesothelioma tumor cells. Generally, it takes many years between asbestos exposure and the development of adverse health complications, as the fibers will slowly irritate and inflame the internal tissue over time until symptoms appear.

Many of those exposed to asbestos have successfully received compensation from asbestos product manufacturers for injuries and illnesses such as pleural mesothelioma. If you believe you were wrongfully exposed to asbestos and have developed an asbestos-related health complication, we urge you to complete the brief form on this page. We’ll rush you a complimentary mesothelioma and asbestos exposure information packet detailing advancements in the treatment of pleural mesothelioma, top doctors and cancer centers, and mesothelioma attorney options you may have.
Don't Let Time Get in the Way!

Don't let time prevent you from taking legal action if you have been diagnosed with malignant pleural mesothelioma as a result of asbestos exposure. Every state establishes set timeframes for filing lawsuits for an asbestos related injury. These timeframes are also known as the state statutes of limitation. The deadlines established in the statutes are fixed so it is important to consult with a legal professional soon after the onset of an asbestos related illness to determine what, if any action may be appropriate.
Exposure To Asbestos

Exposure To Asbestos

Exposure To Asbestos - Exposure to asbestos particles is one of the principal causes of mesothelioma cancer, also known as asbestos cancer. As a naturally occurring mineral with useful commercial applications, asbestos is found in plumbing, insulation and other building materials and products.

Through the liberal commercial use of this material, most people in the United States and other industrial nations have been or will be exposed to loose, airborne particles in their work or home environments, this exposure can create significant health hazards.
 
Commercial Applications
Over 700,000 schools and buildings in the United States today contain asbestos insulation as reported by the US Environmental Protection Agency. Asbestos exposure doesn't stop there, however. Asbestos is often found in ship yards, manufacturing facilities, railway facilities and construction sites. Blue collar workers are at the highest risk for developing mesothelioma due to occupational exposure. They typically work in aluminum plants, oil refineries, chemical plants, mines, factories, shipyards, construction sites and railroads. Employees at insulation and gas mask manufacturing facilities are also at risk. The occupations most widely affected are miners, factory workers, railroad workers, ship builders and construction workers - especially those who install asbestos-containing insulation. Sometimes family members related to the workers receive second hand exposure to asbestos from the dust and fibers that were brought home on the workers clothes and also become at risk for contracting mesothelioma.

There are six different types of asbestos: chrysotile, amosite, crocidolite, tremolite, anthophyllite and actinolite. These six mineral types are divided into two classifications, serpentine and amphibole. Chrysotile is the only mineral in the serpentine class. As known carcinogens both classes of asbestos can cause mesothelioma.

In the United States, chrysotile was the most commonly used asbestos mineral, and is known for its curly fibers that can be easily woven into fabrics. Applications of chrysotile include drywall compound, plaster, vinyl floor tiles, roofing materials, acoustic ceilings, fireproofing, caulk, brake pads and shoes, stage curtains, fire blankets and dental cast linings.

Amosite and crocidolite are the other more common asbestos minerals used, though their application is not as extensive as chrysotile. Products manufactured out of these asbestos minerals include insulation board, ceiling tiles and casing for water services.

In the past ten years, trace amounts of asbestos have been found in talc, a leading ingredient in crayons.

Exposure and Health Risks
The extensive use of asbestos across many different industries exposes not only those individuals working in the manufacturing of raw asbestos or working with asbestos-related products, but also individuals who may have asbestos in their homes, churches or schools. Further, asbestos particles may cling to the clothing or hair of an individual working with asbestos and potentially contaminate others.

Though chrysotile is the most common form of asbestos used in products and is a known carcinogen, amosite and crocidolite asbestos are the most hazardous to health. All types of asbestos can linger in an individual’s lungs for many years after exposure, but amosite and crocidolite are the most persistent, lingering particles.

There is a higher risk for individuals working in asbestos-related environments, though many individuals with minimal exposure can also have damage that can lead to mesothelioma cancer or other diseases.

Although asbestos exposure may have hit its peak from the turn of the twentieth century through the 1970s, many individuals are still being subjected to asbestos particles. Arguably, the most recent and tragic mass exposure resulted from the attacks on 9/11, where tons of asbestos particles were released into the air, harming thousands of rescue workers and individuals living near Ground Zero. Diagnosed with asbestos cancer due to their prolonged, persistent exposure, many brave firefighters, police and rescue workers continue to suffer.

Further, many individuals continue to be exposed to asbestos in older homes. With the boom of Do-It-Yourself projects, many homeowners are tackling renovations without knowing the potential health risks. Attempting renovations in these environments may disturb asbestos causing it to become airborne and inhaled. Without knowledge of where asbestos may be located in these homes, there is a significant risk of accidental exposure, and any homeowner should have professional do a thorough inspection before any projects begin. Removal should always be handled by a professional contractor and should not be attempted by homeowners.

One of the groups hardest hit from asbestos-related diseases are America’s veterans. All branches of the United States military used equipment, gear and products laden with asbestos, unwittingly exposing young men and women between the 1940s and late 1970s. Most veterans repeatedly exposed to asbestos suffer from mesothelioma disease.

For over one hundred years, almost every product that we can come in contact with may have been produced with asbestos components. From decorative household items, to products manufactured to protect firefighters, to dental products, asbestos has been the silent, deadly part of recent American industry.

Asbestos Related DiseaseSome research points to the fact that inhaled asbestos fibers cause a physical irritation resulting in mesothelioma rather than the cancer being caused by a reaction that is more chemical in nature. As fibers are inhaled through the mouth and nose they are cleared from the body by adhering to mucus in the nose, throat and airways and then get expelled by coughing or swallowing. The Amphibole fibers (long and thin) do not clear as easily and it is therefore thought that they can embed into the lining of the lungs, chest or stomach causing scarring and inflammation which increases the risk for mesothelioma cancer. Mesothelioma symptoms can be detected as early as ten years after exposure and can incubate as long as forty years.

Asbestosis (scar tissue in the lungs) or mesothelioma lung cancer can also be caused by the inhalation of asbestos fibers. In fact, people exposed to asbestos are seven times more likely to develop lung cancer over the general public. Workers who sustain high levels of asbestos exposure are more likely to die from asbestosis, lung cancer or mesothelioma than any other disease. It is also believed that the action of coughing up and swallowing asbestos could contribute to a form of mesothelioma originating in the abdomen called peritoneal mesothelioma. This disease has been found to exist in other organs of the body as well such as the larynx, pancreas and colon, but those instances are extremely limited compared to lung cancer incidents.

The chance of developing mesothelioma is in direct proportion to the duration and amount of asbestos exposure that an individual sustains. Those who are exposed to high levels of asbestos at a young age, for long periods of time have a greater risk of being diagnosed with mesothelioma than those who have short, low level exposure. Another important consideration is that the mesothelioma latency period is very long. Often, twenty to forty years can elapse from the time of exposure to diagnosis. Genetic factors can also play a role which explains why not everyone exposed to asbestos develops an asbestos related disease

source : http://www.mesothelioma.com/mesothelioma/risk-factors/asbestos-exposure.html

Mesothelioma Causes


What Causes Mesothelioma?


Mesothelioma is a cancer that occurs in the mesothelium, a thin membrane encompassing the body’s internal organs and cavities. Mesothelioma is caused by asbestos exposure. Asbestos fibers that are inhaled through the mouth and nose may eventually become embedded in the lining of the lungs, causing harmful inflammation of the pleura and resulting in mesothelioma or asbestosis (scar tissue formation in the lungs). It has also been found that swallowing asbestos fibers could contribute to a form of the malignancy originating in the abdomen known as peritoneal mesothelioma.

Mesothelioma generally results from occupational asbestos exposure but there are instances of environmental exposure that can also cause the disease. Oftentimes a family member can be affected indirectly by second hand exposure from an asbestos worker’s soiled work clothes.

Asbestos was an effective insulation material. It was used liberally in commercial and industrial products in the United States until being regulated in a joint effort between the Consumer Product Safety Commission and the Environmental Protection Agency in 1989. Occupational exposure was common among workers who encountered these products in many industries including shipbuilding, power plants, and other industrial settings.

Asbestos insulation workers appear to have the highest rate of asbestos related disease. One study reports that almost six percent of asbestos workers fall victim to mesothelioma or experience respiratory symptoms. Asbestos insulation workers are over 300 times more likely to be diagnosed with mesothelioma than those with no exposure history.

How does exposure to asbestos cause mesothelioma?


Asbestos fibers are microscopic, though they are also quite durable. For this reason, asbestos was used in a number of different industrial compounds to enhance strength and resistance to temperature extremes- two properties at which the mineral is highly adept. Asbestos exposure most often occurred among individuals who worked extensively with asbestos or asbestos-containing materials. Friable asbestos (meaning loose or airborne fibers) is easily inhaled- often without the exposed person realizing.


When inhaled, asbestos lodges easily in the outer lung tissue and within the mesothelium. The mesothelium is a thin membrane of cells which produces a lubricating fluid on the surface of the organs. This lubricant allows the lung and other internal structures to expand, contract, and move freely without friction in the body cavity. There is a great deal of latency associated with mesothelioma between exposure to asbestos and the onset of symptoms. Over time (often 40 or 50 years) asbestos irritates this tissue, causing inflammation and malignant scar tissue plaques on the surface of the mesothelium. These plaques are the foundation of the mesothelioma tumor.

Pleural mesothelioma is the most common variety of the disease and forms on the pleural membrane, which surrounds the lung and chest cavity. Peritoneal mesothelioma is less common and forms on the surface of the peritoneum, a thin membrane surrounding the abdominal cavity. Pericardial mesothelioma is the least common variety of the disease and forms in the cardiac cavity that envelops the heart, a mesothelial membrane known as the pericardium.

Inhaled asbestos fibers are known to be the cause of pleural mesothelioma, whereas ingested asbestos fibers are the cause of peritoneal mesothelioma. While the exact causal nature between asbestos and pericardial mesothelioma is not known, physicians and cancer researchers surmise asbestos fibers in the blood stream lodge in the outer layers of the heart’s ventricles and lodge in the pericardium. Once asbestos fibers reach the surface of the peritoneum or pericardium, the inflammation process is essentially the same as it is on the surface of the pleura.

Primary workplace exposure to the mineral was common in naval shipyards, power plants, railroad infrastructure, and other industrial jobsites. However, asbestos-related mesotheliomas have also been diagnosed in spouses or children of those exposed to asbestos. Workers often brought home dangerous asbestos fibers on their clothing, hair, or person. Those who came into contact with these fibers on the person or their clothing have developed mesothelioma as a result.
Other Contributing Factors

Mesothelioma is also causally associated with a few other factors, but many of these are attributed to the development of mesothelioma in conjunction with exposure to asbestos.
Smoking

Those who smoke are at a higher risk of mesothelioma, though smoking is more commonly associated with traditional lung carcinomas. Smoking tends to enhance risk even further in those who were also exposed to asbestos.
Radiation Exposure

While extremely rare, some mesothelioma patients attribute their diagnosis to exposure to radiation rather than exposure to asbestos. Radiation tends to transform and mutate cell growth patterns and is more commonly associated with brain and blood cancers.
Carbon Nanotubes

Research is extremely preliminary in this study, but some laboratory studies indicate a molecular similarity between asbestos mineral fibers and carbon nanotubes. Tests indicate a pronounced risk of mesothelioma in some laboratory animals implanted with carbon nanotubes.
What Should I do if I have been diagnosed with Mesothelioma?

Many of those diagnosed with mesothelioma wonder if asbestos exposure is to be blamed for their illness. Asbestos was used in thousands of commercial and industrial products. These include, but are not limited to roofing material, insulation compounds, joint compounds, cements, siding, floor and ceiling, tiles, glue, and any other product designed specifically to withstand heat and temperature extremes.

If you worked with one of these products and have been diagnosed with mesothelioma, it is highly likely asbestos is the cause of your illness. To help you in recovering costs for mesothelioma treatment as well as damages to assist your family, you should speak with a well-versed asbestos attorney to determine if you’re eligible for compensation. Court documents now indicate many of these product manufacturers were well aware of the hazards which asbestos posed but continued to endanger employees and the public by exposure to the mineral. To learn more about the relationship between asbestos exposure and mesothelioma, or to find out if you’re eligible for financial compensation for your illness, please fill out the brief form on this page.


Mesothelioma Causes

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Mesothelioma Risk Factors

Mesothelioma Risk Factors

What are the risk factors for malignant mesothelioma?

There are several risk factors that increase the likelihood that a person will develop mesothelioma. The primary risk factor is asbestos exposure. Exposure to this very harmful substance can significantly enhance the chances of contracting the disease. Smoking does not have a direct causal relationship with mesothelioma but is a significant compounding factor and increases the chances of developing the disease. Other less common secondary factors include exposure to radiation, zeolite, simian virus 40 (SV40) and erionite. We discuss each of these risk factors in more detail below. Please click on the links to learn more about each mesothelioma risk factor.

Exposure to Asbestos

Exposure to asbestos is the leading risk factor associated with mesothelioma. Asbestos is an insulating material comprised of magnesium-silicate mineral fibers. It was favored by builders and contractors for many years for its low heat conductivity and resistance to melting and burning. Since researchers have identified more and more links between mesothelioma and exposure to asbestos, the material is now less widely used. Prior to this discovery, however, millions of Americans have experienced serious exposure to this harmful substance.

Smoking and Mesothelioma
Smoking alone is not linked to mesothelioma, but smokers who are exposed to asbestos have a much higher chance of developing asbestos lung cancer (as much as fifty to ninety percent higher) and as much as double the risk of developing mesothelioma.

Less Common Mesothelioma Risk Factors


Radiation

Thorium dioxide (Thorotrast), a substance used in x-ray tests in the past has reported links to pleural mesothelioma and peritoneal mesothelioma. The use of Thorotrast has been discontinued for many years due to this discovery.

Zeolite
Some mesothelioma cases in the Anatoli region within Turkey have been linked to Zeolite, a silica based mineral with chemical properties similar to asbestos found in the soil there.

Simian Virus 40 (SV40)

Some scientists have found the simian virus 40 (SV30) in mesothelioma cells from humans and have been able to create mesothelioma in animals with the virus. The relationship between this virus and mesothelioma is still unclear, however, and further research is being conducted to gain clarity on this potential link.

Erionite Exposure
Erionite is a naturally occurring mineral that possesses properties that are very similar to those of asbestos. There have been several documented cases of mesothelioma in indivuduals living near large erionite deposits.

Carbon Nanotubes
Researchers continue to evaluate nanotube exposure as a possible risk factor for mesothelioma even though scientists have not expressed immediate concern.

source : http://www.mesothelioma.com/mesothelioma/risk-factors/asbestos-exposure.htm